How about scaling up the interface

I just was sent this link which shows the creative use of a touchscreen. For one thing it is very creative and pretty. But it also set me thinking. Why on earth are we fiddling around with a silly little mouse getting RSI? Is it not much more natural to be able to manipulate your desktop using larger motions? Of course you don't want a computer this size everywhere, but this being at my desk would not seem such a silly idea at all.
PS: I just read that the operating system and programmes wouldn't be on the computer itself but on a datastick. That of course already exists and makes perfect sense. Finally all my programmes with me, everywhere....